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All biomarkers
Hepatic / liver

AST (aspartate aminotransferase)

Measured in U/L · LOINC 1920-8

Reference ranges

Optimal
1025 U/L
functional-medicine target
Standard
1040 U/L
lab reference range

Optimal ranges are tighter than standard lab ranges and reflect functional-medicine targets, not the populations they were derived from. Reference bands depend on sex, age, and circumstance — Juno's lab analysis layers your profile context onto the printed range when you paste a value.

Peptide relevance

Read alongside ALT (existing entry) — together they characterize hepatic vs. extrahepatic causes of elevation. AST is less liver-specific than ALT: muscle injury, intense exercise, and red blood cell turnover all raise AST. AST/ALT ratio >2 with high MCV suggests alcohol; ratio <1 with both elevated suggests metabolic-associated steatotic liver disease (MASLD). BPC-157 has shown hepatoprotective effects in animal models — may lower or prevent rises. GLP-1 agonists lower AST modestly in NAFLD/MASH patients. KEY CONFOUNDERS: eccentric training in last 48-72h, statins (rare), AAS (NOT peptides, common co-use).

Have a recent AST (aspartate aminotransferase) value?

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