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All biomarkers
Nutritional

Folate (serum)

Measured in ng/mL · LOINC 2284-8

Reference ranges

Optimal
1020 ng/mL
functional-medicine target
Standard
317 ng/mL
lab reference range

Optimal ranges are tighter than standard lab ranges and reflect functional-medicine targets, not the populations they were derived from. Reference bands depend on sex, age, and circumstance — Juno's lab analysis layers your profile context onto the printed range when you paste a value.

Peptide relevance

Critical for methylation, DNA synthesis, and red blood cell formation. Paired with B12 — folate deficiency masks B12 deficiency in CBC by 'fixing' the macrocytosis, hiding the neurological B12 issue. Always interpret folate alongside B12 + homocysteine. Folic acid (synthetic) vs methylfolate (active) matters for MTHFR polymorphism carriers — homozygous 677TT users may have suboptimal conversion and benefit from methylfolate over folic acid. No direct peptide effects documented in common stacks. KEY CAVEATS: serum folate reflects recent intake; RBC folate (separate test) is the better long-term marker but rarely ordered. Folic acid fortification in US grain products keeps most users above the deficiency floor.

Have a recent Folate (serum) value?

Paste it on the lab analysis page. Juno reads your active stack + (if shared) your medications and conditions, and surfaces plausible contributors with citations. Doesn't diagnose.

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