Reference ranges
Optimal ranges are tighter than standard lab ranges and reflect functional-medicine targets, not the populations they were derived from. Reference bands depend on sex, age, and circumstance — Juno's lab analysis layers your profile context onto the printed range when you paste a value.
Peptide relevance
Higher = better, generally. GLP-1 agonists (tirzepatide, semaglutide) modestly raise HDL-C (~2-5%, weight-loss driven). CJC-1295 + Ipamorelin: minimal documented effect. Anabolic-androgenic steroids (NOT peptides, often co-used) reliably SUPPRESS HDL — a 30-50% drop in HDL is a hallmark of cycling AAS, important to flag if the user discloses use. Tirzepatide trials show HDL gains modest relative to weight loss. Exercise (especially aerobic) is the strongest HDL-raising non-pharmacological lever — confounds peptide-attribution if user is also ramping cardio.
Peptides that influence this marker
Documented to affect this marker. Click through for the full evidence-tiered profile.
Have a recent HDL cholesterol (HDL-C) value?
Paste it on the lab analysis page. Juno reads your active stack + (if shared) your medications and conditions, and surfaces plausible contributors with citations. Doesn't diagnose.
Sign-in required. The analysis is saved to your private history and audit-logged.