Reference ranges
Optimal ranges are tighter than standard lab ranges and reflect functional-medicine targets, not the populations they were derived from. Reference bands depend on sex, age, and circumstance — Juno's lab analysis layers your profile context onto the printed range when you paste a value.
Peptide relevance
SHBG binds testosterone and estradiol — without it you cannot interpret total testosterone correctly. High SHBG (often from hyperthyroidism, low calories, or aging) lowers free T even when total T looks fine. Low SHBG (from insulin resistance, obesity, or androgen use) inflates free T. Exogenous androgens including TRT suppress SHBG within 4-8 weeks; CJC-1295 + Ipamorelin have no documented SHBG effect. Tirzepatide / Semaglutide raise SHBG modestly as weight drops (insulin sensitivity improvement). RANGES SHOWN ARE FOR ADULT MEN; adult women are typically 20-130 nmol/L.
Have a recent SHBG (sex hormone-binding globulin) value?
Paste it on the lab analysis page. Juno reads your active stack + (if shared) your medications and conditions, and surfaces plausible contributors with citations. Doesn't diagnose.
Sign-in required. The analysis is saved to your private history and audit-logged.