Guided peptide programs — phased, sequenced, honest.
Protocols are the editorial layer between “which peptides exist for this concern” and “here is what I am taking.” Each one walks through a goal in phases — cofactor restoration before mitochondrial layering, acute stabilization before subacute repair — with decision criteria so you know when to advance, when to pivot, and when to stop. One click adds the whole program to your stack with phase-aware future-dated entries.
Stack multiple protocols when you have multiple concerns — your stack page de-dupes overlapping peptides and surfaces interaction warnings across the union.
Foundations
Everyday health and performance programs that apply broadly across users and life stages.
- Mitochondrial + cofactor stack
Energy & Vitality
Persistent low energy is usually a symptom, not a diagnosis. Sleep, thyroid, B-vitamin deficiency, anemia, depression, and sleep apnea are the common upstream causes — peptides are not the diagnostic. If you haven't worked through those with your doctor yet, start there.
3 phases4 peptidesOpen protocol - Pineal-axis + sleep-architecture peptides
Sleep Optimization
Sleep is the most upstream lever for almost every concern peptide users come in with — energy, cognition, recovery, mood, body composition, immune function all run downstream of sleep. The peptide-side evidence for sleep, however, is the weakest in the Juno catalog. Most of it comes from Russian and Soviet research that Western clinical trials have not replicated. Be honest with yourself about that before starting.
2 phases2 peptidesOpen protocol - Nootropic + neurorestorative stack
Cognitive Sharpness
Cognitive complaints are tricky because they are usually downstream of something more fundamental. Sleep debt, thyroid dysfunction, B12 or iron deficiency, depression, sleep apnea, vascular health, undiagnosed inflammatory burden — any of these will present as "brain fog" or declining sharpness, and none of them are fixed by peptides. Before starting this protocol, work through a proper differential with your clinician.
3 phases3 peptidesOpen protocol - GLP-1/GIP metabolic foundation + GH-axis lean-mass layer
Body Composition
Body composition is the highest-traffic goal in the peptide community and the one where evidence quality varies most across the stack you actually end up running. The FDA-approved GLP-1/GIP drugs (semaglutide, tirzepatide) have Tier 1 evidence for weight loss — the SURPASS and SURMOUNT trials are real, large, replicated. Everything users layer on top of that (GH-axis peptides for "lean mass sparing," AOD-9604 for "targeted lipolysis") is community practice with much weaker evidence.
3 phases3 peptidesOpen protocol - mTOR pulse + NAD+ substrate + senolytic layer
Longevity
Longevity is the most-claimed and least-evidenced goal in the peptide community. Be honest with yourself before starting this protocol: nothing here is a guarantee of a longer life. The closest thing we have to modern human evidence for any of these interventions is the PEARL Phase 2 trial (2024) for off-label rapamycin in healthy adults — and the results were equivocal. The mechanistic stories for rapamycin (mTOR inhibition), NAD+ precursors (cellular redox), and pineal peptides (telomerase, melatonin signaling) are real. The translation from "raises blood marker X" to "actually lives longer" is not.
3 phases4 peptidesOpen protocol - Topical + systemic collagen / aesthetic layer
Skin & Aesthetics
Skin & Aesthetics is the only V1 Juno protocol with primarily cosmetic rather than medical goals. The peptide evidence here is unusually phase-dependent: topical GHK-Cu has solid dermatology evidence for skin-appearance markers (collagen synthesis, fine lines, hair density) at cosmetic-grade concentrations. Systemic injectable peptides for skin (the Glow blend, GHK-Cu SubQ) are community practice with much thinner data. Melanotan for cosmetic tanning is editorially the most fraught peptide in the V1 catalog — the use case sits in tension with the well-established melanoma-risk story.
3 phases3 peptidesOpen protocol - Thymic + antioxidant + antimicrobial peptide stack
Immune Resilience
This protocol is for IMMUNE RESILIENCE — building robustness over months, not treating acute illness. If you currently have a cold, flu, COVID, or any other active infection, this is the wrong tool right now. Peptides do not replace antivirals, antibiotics, antifungals, or the standard medical treatment of infection. Resilience work is what you do BEFORE you need it.
2 phases4 peptidesOpen protocol
Recovery & repair
Targeted tissue and mucosal repair work — what you reach for when something specific needs to heal.
- Soft-tissue + tendon repair stack
Recovery from Injury
Soft-tissue and tendon recovery is where peptide therapy has the most enthusiastic community evidence — and the smallest gap between enthusiasm and the human data. The two core peptides in this protocol (BPC-157 and TB-500) have rodent and in-vitro evidence for tissue repair, but essentially no human RCT data for the indications they're used for. Be honest with yourself about that.
3 phases3 peptidesOpen protocol - Mucosal-repair + anti-inflammatory stack
Gut Healing
This protocol is for ADJUNCTIVE gut-healing work alongside diet and clinical care. It is NOT first-line. If you have overt rectal bleeding, melena (black tarry stools), persistent severe abdominal pain, unexplained weight loss, fever, iron-deficiency anemia, or a family history of colorectal cancer, the answer is a gastroenterologist and a workup — not peptides. Peptides should never be used to mask symptoms that warranted a scope.
3 phases3 peptidesOpen protocol
Life stage
Demographic-specific protocols for users in particular reproductive or hormonal windows. Each leads with the standard-of-care framing (HRT, REI, OB-GYN) before adjunct peptide work.
- Preconception cofactor + specialist-guided adjuncts (both partners)
Fertility Planning
This protocol is for the PRECONCEPTION window — actively trying to conceive (TTC) or in the preparation runway 3-6 months before TTC starts. It covers BOTH partners: male-factor and female-factor infertility contribute roughly equally to fertility concerns, and the standard pattern of outsourcing all the work to the female partner misses half the relevant biology.
2 phases3 peptidesOpen protocol - Cofactor restoration → tissue repair → GH-axis (post-weaning)
Postpartum Recovery
This protocol covers the postpartum recovery window — the months after birth, when nutrient stores are depleted, tissue is healing, sleep is fragmented, and body composition needs are different from any other life stage. It is structured around a load-bearing safety distinction: PHASE 1 (B12 + B-complex cofactor restoration) is SAFE to run while breastfeeding; PHASE 2 (BPC-157 tissue repair) and PHASE 3 (CJC/Ipa GH-axis) are NOT — those peptides have no human breastfeeding safety data and should be deferred until weaning is complete.
3 phases4 peptidesOpen protocol - HPG-axis stimulation + GH-axis layer (male midlife)
Andropause Support
This protocol is for men in midlife with symptomatic low-T presentation — fatigue, loss of morning erections, declining libido, mood flatness, reduced muscle mass and strength despite training — who want to explore peptide-based options BEFORE committing to traditional testosterone replacement therapy (TRT). The decision between TRT and peptide-based HPG stimulation is not minor: TRT shuts down endogenous testicular function (a one-way door for many users; restoring fertility after years on TRT is difficult and not guaranteed). Peptide-based HPG stimulation (kisspeptin) preserves the upstream signaling that drives natural testosterone production.
3 phases3 peptidesOpen protocol - Cofactor + NAD+ substrate + GH-axis (adjunct to HRT)
Menopause Support
This protocol is for women in perimenopause or postmenopause who want peptide-based ADJUNCT support alongside (or in place of) hormonal management. The most important editorial point: hormone replacement therapy — HRT, also called menopausal hormone therapy (MHT) — is the evidence-based first-line treatment for vasomotor symptoms (hot flashes, night sweats), genitourinary syndrome of menopause, perimenopausal mood symptoms, and bone density preservation. The 2022 NAMS Position Statement and the Women's Health Initiative re-analyses have largely re-positioned HRT as the appropriate first-line therapy for symptomatic women within ~10 years of menopause without contraindications. This protocol is NOT a substitute for that conversation with your gynecologist or menopause-specialist clinician.
3 phases3 peptidesOpen protocol
Specialized
Niche but important contexts that don't fit the broader categories.
- Anxiolytic + neurotrophic peptide stack
Anxiety + Mood Support
This protocol is for SUB-CLINICAL anxiety and low mood — the everyday load that doesn't meet diagnostic criteria for a mental-health condition but still degrades quality of life: persistent work-related anxiety, situational stress around life transitions, low-grade mood flatness without anhedonia or suicidal ideation. It assumes lifestyle anchors are in place (sleep, movement, daylight exposure, real-life social contact) or are being worked on alongside.
2 phases2 peptidesOpen protocol - Off-season tissue + GH-axis → peak metabolic + endurance (WADA-banned throughout)
Competition Prep
This protocol is for athletes preparing for competition who are using community-knowledge peptide stacks. The single most important framing for this entire surface: EVERY PEPTIDE IN THIS PROTOCOL IS ON THE WORLD ANTI-DOPING AGENCY (WADA) PROHIBITED LIST, both in-competition and out-of-competition. Users running this protocol while subject to drug-tested federation rules are violating those rules. The protocol does NOT pretend otherwise.
2 phases4 peptidesOpen protocol